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On Monday, September 17, POISON singer Bret Michaels's 'Lifestyle Collection' debuts at. This very special collection contains items for everyday use — including the first-ever Bret Michaels candle, inspirational cards (both digital and paper), guitars, and holiday cards, among others — as well as unique household and outdoor goods. A portion of proceeds to benefit a wide array of charities via Bret's Life Rocks Foundation. Life Rocks Foundation is a unique dollar-in-dollar-out foundation that gives back to multiple causes, including diabetes research, wounded soldiers, and animals in need (pet shelters), among others. 'It is a foundation that I set up, and I find a cause in each place that I play, and we donate money,' he told Digital Journal. Michaels is a multi-platinum global superstar who has turned his passion for music into a multi-faceted brand that encompasses record-breaking touring sales, reality TV stardom, legendary songs that have sold over 32 million records, product endorsements as well as being a devoted philanthropist, all supported and followed by three generations of loyal fans. Bret was born in Butler, Pennsylvania on March 15, 1963.

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Rising to fame as the frontman of POISON, one of rock's most iconic and enduring bands, he helped define rock 'n' roll on the Sunset Strip. POISON's massive success includes selling over 30 million records worldwide and numerous hit singles. Bret's solo career has charted its own course with multiple solo albums. His last album, 'Custom Built', included guest appearances by Joe Perry ( AEROSMITH) Loretta Lynn, Jimmy Buffett, Ace Frehley ( KISS), Michael Anthony ( VAN HALEN) and members of LYNYRD SKYNYRD.

When this multi-talented performer is not touring, he can be found both in front of and behind the camera as a director, producer and a reality TV superstar. Shows like 'Rock Of Love With Bret Michaels' on VH1, 'Life As I Know It' and Bret has also starred in and won Donald Trump's NBC hit 'Celebrity Apprentice'.

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BACKGROUND: Ambient air pollution is associated with numerous adverse health outcomes, but the underlying mechanisms are not well understood; epigenetic effects including altered DNA methylation could play a role. To evaluate associations of long-term air pollution exposure with DNA methylation in blood, we conducted an epigenome-wide association study in a Korean chronic obstructive pulmonary disease cohort (N = 100 including 60 cases) using Illumina's Infinium HumanMethylation450K Beadchip. Annual average concentrations of particulate matter ≤ 10 μm in diameter (PM10) and nitrogen dioxide (NO2) were estimated at participants' residential addresses using exposure prediction models. We used robust linear regression to identify differentially methylated probes (DMPs) and two different approaches, DMRcate and comb-p, to identify differentially methylated regions (DMRs).

En espanol noticias RESULTS: After multiple testing correction (false discovery rate.